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Effect of the nonsteroidal antiestrogen ZK 119.010 on growth and metastasis of the EnDA endometrial carcinoma

Horn, D. W. and Vollmer, G. and Angerer, E. von and Schneider, M. R. (1994) Effect of the nonsteroidal antiestrogen ZK 119.010 on growth and metastasis of the EnDA endometrial carcinoma. International journal of cancer. Journal international du cancer 58 (3), pp. 426-429.

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Abstract

For patients with disseminated endometrial cancer the prognosis is poor. Radiotherapy, chemotherapy or high-dose progestins have been of limited value in the clinic, with low response rates and a usually short duration. Because of the role of estrogen in the etiology of this disease, a rationale exists for therapies using estrogen antagonists. In order to test this strategy, we used the EnDA ...

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Item Type:Article
Date:1994
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Identification Number:
ValueType
8050824PubMed ID
Classification:
NotationType
Adenocarcinoma/drug therapyMESH
AnimalsMESH
Cell Division/drug effectsMESH
Endometrial Neoplasms/drug therapyMESH
Estrogen Antagonists/pharmacologyMESH
EstrogensMESH
FemaleMESH
Indoles/pharmacologyMESH
Lung Neoplasms/drug therapyMESH
Lymphatic MetastasisMESH
Neoplasm TransplantationMESH
Neoplasms, Hormone-Dependent/drug therapyMESH
Organ Size/drug effectsMESH
OvariectomyMESH
RatsMESH
Rats, Inbred StrainsMESH
Receptors, Estrogen/drug effectsMESH
Tamoxifen/pharmacologyMESH
Uterus/anatomy & histologyMESH
Subjects:500 Science > 570 Life sciences
500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Owner: Prof. Armin Buschauer
Deposited On:11 Dec 2008 17:32
Last Modified:05 Aug 2009 13:48
Item ID:4759
Owner Only: item control page
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