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Antitumour activity of coumarin in prostate and mammary cancer models

Angerer, E. von and Kager, M. and Maucher, A. (1994) Antitumour activity of coumarin in prostate and mammary cancer models. Journal of Cancer Research and Clinical Oncology 120 Suppl, S14-S16.

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Abstract

The antineoplastic and antimetastatic activities of coumarin were evaluated in transplanted prostate tumours of the rat. The growth of Noble Nb-R prostate tumours was strongly inhibited by coumarin (40 mg/kg; administered three times per week), whereas the hormonally more sensitive Dunning R3327-G rat prostate carcinoma did not respond. Coumarin was also shown to possess antimetastatic activity ...

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Item Type:Article
Date:1994
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Identification Number:
ValueType
8132695PubMed ID
Classification:
NotationType
Adenocarcinoma/drug therapyMESH
AnimalsMESH
Coumarins/therapeutic useMESH
Disease Models, AnimalMESH
FemaleMESH
Lung Neoplasms/prevention & controlMESH
MaleMESH
Mammary Neoplasms, Experimental/drug therapyMESH
Neoplasm TransplantationMESH
Neoplasms, Hormone-Dependent/drug therapyMESH
OrchiectomyMESH
Prostatic Neoplasms/drug therapyMESH
RatsMESH
Subjects:500 Science > 570 Life sciences
500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Prof. Armin Buschauer
Deposited On:03 Dec 2008 15:20
Last Modified:05 Aug 2009 13:48
Item ID:4765
Owner Only: item control page
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