Startseite UB

[DL-1,2-bis(2-hydroxyphenyl)ethylenediamine]dichloroplatinum(II), a new compound for the therapy of ovarian cancer

Müller, Richard and Gust, Ronald and Bernhardt, Günther and Keller, Christoph and Schönenberger, Helmut and Seeber, Siegfried and Osieka, Reinhardt and Eastman, Alan and Jennerwein, Margaretha (1990) [DL-1,2-bis(2-hydroxyphenyl)ethylenediamine]dichloroplatinum(II), a new compound for the therapy of ovarian cancer. Journal of cancer research and clinical oncology 116 (3), pp. 237-244.

[img]
Preview
PDF
Download (837kB)

at PubMed


Abstract

The synthesis of diastereoisomeric [1,2-bis(2-hydroxyphenyl)ethylenediamine]dichloroplatinum(II) complexes, DL-3-PtCl2 and meso-3-PtCl2, and their evaluation on the hormone-independent, human MDA-MB231 breast cancer cell line, on the cisplatin-sensitive and -resistant L1210 leukemia cell line, on the cisplatin-resistant human NIH:OVCAR 3 ovarian cancer cell line, on the P-388 leukemia of the ...

plus


Export bibliographical data



Item Type:Article
Date:1990
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Retired Professors > Prof. Schönenberger
Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Identification Number:
ValueType
2370248PubMed ID
Classification:
NotationType
AnimalsMESH
Antineoplastic Agents/pharmacologyMESH
Carcinoma, Ehrlich Tumor/drug therapyMESH
Cisplatin/pharmacologyMESH
Drug ResistanceMESH
FemaleMESH
HumansMESH
MiceMESH
Organoplatinum Compounds/pharmacologyMESH
Ovarian Neoplasms/drug therapyMESH
Tumor Cells, CulturedMESH
Subjects:500 Science > 570 Life sciences
500 Science > 540 Chemistry & allied sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Owner: Universitätsbibliothek Regensburg
Deposited On:14 Jan 2009 13:26
Last Modified:13 Mar 2014 18:32
Item ID:4829
Owner Only: item control page

Downloads

Downloads per month over past year

  1. University

University Library

Publication Server

Contact person
Gernot Deinzer

Telefon 0941 943-2759
Contact