Dove, Stefan and Franke, R. (1989) Some Problems of the Interpretation of Receptorologic Data in QSAR Work. In: Fauchere, J. L., (ed.) QSAR: Quantitative Structure-Activity Relationships in Drug Design. Progress in clinical and biological research, 291. A. R. Liss Inc., New York, 31 - 35. ISBN 0-8451-5141-X.
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Abstract
An extended model of the b-adrenergic receptor and adenylate cyclase activation by b-agonists, including receptor conformational changes and ternary complex formation with effector G protein are used to illustrate problems in QSAR.
| Item Type: | Book Section | ||||
|---|---|---|---|---|---|
| Institutions: | Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer) | ||||
| Identification Number: |
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| Subjects: | 500 Science > 570 Life sciences 500 Science > 540 Chemistry & allied sciences | ||||
| Status: | Published | ||||
| Refereed: | No this document will not be refereed | ||||
| Created at the University of Regensburg: | No | ||||
| Owner: | Prof. Dr. Stefan Dove | ||||
| Deposited On: | 21 Jan 2009 18:47 | ||||
| Last Modified: | 05 Aug 2009 15:50 | ||||
| Item ID: | 5413 |
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