Startseite UR

Estrogenic activity: An example of considering effectuation models in biological data interpretation and QSAR

Dove, Stefan ; Schönenberger, Helmut



Zusammenfassung

On a preliminary series of 1,2-dialkylated 1,2-bis(hydroxyphenyl)ethanes and -ethenes, the interrelations of affinity (pKD on estrogen receptor from calf uterus cytosol) and activity parameters (maximal estrogenic activity emax compared to estrone = 1, the Hill coeff. nH, and pD2 = log ED50) were investigated by principal component anal., leading to some first results about the structural dependence of the different steps of ligand-receptor interactions.


Nur für Besitzer und Autoren: Kontrollseite des Eintrags
  1. Universität

Universitätsbibliothek

Publikationsserver

Kontakt:

Publizieren: oa@ur.de
0941 943 -4239 oder -69394

Dissertationen: dissertationen@ur.de
0941 943 -3904

Forschungsdaten: datahub@ur.de
0941 943 -5707

Ansprechpartner