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Transkriptionelle Regulation von MADDAM/ADAM19

URN to cite this document:
urn:nbn:de:bvb:355-opus-4811
DOI to cite this document:
10.5283/epub.10298
Ehrnsperger, Achim
Date of publication of this fulltext: 14 Mar 2005 06:58


Abstract (German)

MADDAM (Metalloprotease and disintegrin dendritic cell antigen marker) ist ein molekularer Marker zur Unterscheidung von in vitro differenzierten Makrophagen und dendritischen Zellen. MADDAM wird in Monozyten exprimiert und während der in vitro Differenzierung zu Makrophagen herunterreguliert. Dagegen wird MADDAM im Verlauf der in vitro Differenzierung von Monozyten zu dendritischen Zellen ...

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Translation of the abstract (English)

Transcriptional regulation of MADDAM / ADAM19 MADDAM (metalloprotease and disintegrin dendritic antigen marker) is a molecular marker for the in vitro differentiation of monocytes into dendritic cells. MADDAM is strongly expressed during dendritic cell differentiation, whereas the in vitro differentiation of monocytes into macrophages is associated with a downregulation of MADDAM mRNA levels. ...

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