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AMIGOS: a method for the inspection of genomic organisation or structure and its application to characterise and dissect conserved gene arrangements

Merkl, Rainer


In order to identify and to characterise gene clusters conserved in microbial genomes, the algorithm AMIGOS was developed. It is based on a categorisation of genes using a predefined set of gene functions (GFs). After the categorisation of all genes of a genome and based on their location on a replicon, distances between GFs were determined and stored in genome-specific matrices. These matrices ...


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