Merkl, Rainer and Zwick, Matthias (2007) H2r: Identification of evolutionary important residues by means of an entropy based analysis of multiple sequence alignments. BMC Bioinformatics 9, p. 151.
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Other URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2323388/?tool=pubmed
Abstract
BACKGROUND: A multiple sequence alignment (MSA) generated for a protein can be used to characterise residues by means of a statistical analysis of single columns. In addition to the examination of individual positions, the investigation of co-variation of amino acid frequencies offers insights into function and evolution of the protein and residues. RESULTS: We introduce conn(k), a novel ...
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| Item type: | Article | ||||||||||||||||||||||||
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| Date: | 2007 | ||||||||||||||||||||||||
| Institutions: | Biology, Preclinical Medicine > Institut für Biophysik und physikalische Biochemie > Prof. Dr. Rainer Merkl | ||||||||||||||||||||||||
| Identification Number: |
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| Classification: |
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| Dewey Decimal Classification: | 500 Science > 570 Life sciences | ||||||||||||||||||||||||
| Status: | Published | ||||||||||||||||||||||||
| Refereed: | Yes, this version has been refereed | ||||||||||||||||||||||||
| Created at the University of Regensburg: | Partially | ||||||||||||||||||||||||
| Item ID: | 10929 |
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