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Claren, Jörg ; Malisi, Christoph ; Höcker, Birte ; Sterner, Reinhard

Establishing wild-type levels of catalytic activity on natural and artificial (beta alpha)8-barrel protein scaffolds

Claren, Jörg, Malisi, Christoph, Höcker, Birte and Sterner, Reinhard (2009) Establishing wild-type levels of catalytic activity on natural and artificial (beta alpha)8-barrel protein scaffolds. Proceedings of the National Academy of Sciences of the United States of America 106 (10), pp. 3704-9.

Date of publication of this fulltext: 19 Mar 2010 11:10
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Item typeArticle
Journal or Publication TitleProceedings of the National Academy of Sciences of the United States of America
Publisher:NATL ACAD SCIENCES
Place of Publication:WASHINGTON
Volume:106
Number of Issue or Book Chapter:10
Page Range:pp. 3704-9
Date2009
InstitutionsBiology, Preclinical Medicine > Institut für Biophysik und physikalische Biochemie > Prof. Dr. Reinhard Sterner
Identification Number
ValueType
7017727PubMed ID
10.1073/pnas.0810342106DOI
Classification
NotationType
Aldose-Ketose Isomerases/metabolismMESH
Anthranilic Acids/metabolismMESH
Bacterial Proteins/metabolismMESH
BiocatalysisMESH
Catalytic DomainMESH
Crystallography, X-RayMESH
Evolution, MolecularMESH
IsomerismMESH
LigandsMESH
Models, MolecularMESH
Mutant Proteins/metabolismMESH
Protein Structure, SecondaryMESH
Ribosemonophosphates/metabolismMESH
Substrate SpecificityMESH
Thermotoga maritima/enzymologyMESH
KeywordsPHOSPHORIBOSYL ANTHRANILATE ISOMERASE; DIFFERENT METABOLIC PATHWAYS; COMPUTATIONAL ENZYME DESIGN; TRYPTOPHAN BIOSYNTHESIS; THERMOTOGA-MARITIMA; PHOSPHATE SYNTHASE; DIRECTED EVOLUTION; SUBSTRATE-ANALOG; HALF-BARRELS; STRATEGIES; chimeric protein; enzyme design; enzyme evolution; half barrel; TIM barrel
Dewey Decimal Classification500 Science > 570 Life sciences
StatusPublished
RefereedYes, this version has been refereed
Created at the University of RegensburgPartially
Item ID13649

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