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Höcker, Birte ; Claren, Jörg ; Sterner, Reinhard

Mimicking enzyme evolution by generating new (betaalpha)8-barrels from (betaalpha)4-half-barrels.

Höcker, Birte , Claren, Jörg and Sterner, Reinhard (2004) Mimicking enzyme evolution by generating new (betaalpha)8-barrels from (betaalpha)4-half-barrels. Proceedings of the National Academy of Sciences of the United States of America 101 (47), pp. 16448-53.

Date of publication of this fulltext: 22 Mar 2010 08:15
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Item typeArticle
Journal or Publication TitleProceedings of the National Academy of Sciences of the United States of America
Publisher:NATL ACAD SCIENCES
Place of Publication:WASHINGTON
Volume:101
Number of Issue or Book Chapter:47
Page Range:pp. 16448-53
Date2004
InstitutionsBiology, Preclinical Medicine > Institut für Biophysik und physikalische Biochemie > Prof. Dr. Reinhard Sterner
Identification Number
ValueType
11801240PubMed ID
10.1073/pnas.0405832101DOI
Classification
NotationType
Aldose-Ketose Isomerases/metabolismMESH
Aminohydrolases/metabolismMESH
Base SequenceMESH
Cloning, MolecularMESH
DNA, Bacterial/geneticsMESH
Evolution, MolecularMESH
Gene DuplicationMESH
Genes, BacterialMESH
Models, MolecularMESH
Protein Structure, SecondaryMESH
Recombinant Proteins/metabolismMESH
Thermotoga maritima/geneticsMESH
KeywordsDIFFERENT METABOLIC PATHWAYS; DIVERGENT EVOLUTION; STRUCTURAL EVIDENCE; PROTEIN; STABILITY; BARREL; FOLD; HISTIDINE; SEQUENCES; FUSION; chimeric proteins; gene duplication; histidine biosynthesis; TIM-barrel
Dewey Decimal Classification500 Science > 570 Life sciences
StatusPublished
RefereedYes, this version has been refereed
Created at the University of RegensburgYes
Item ID13679

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