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Stereoselective Synthesis of the Quettamine Skeleton

Dirnberger, D. and Wiegrebe, Wolfgang (1990) Stereoselective Synthesis of the Quettamine Skeleton. Archiv der Pharmazie 323, pp. 323-330.

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Date of publication of this fulltext: 08 Jul 2010 04:53


A synthesis of the quettamine skeleton 29 is described comprising ring closure of the diastereomeric phenolic 1-(α-bromobenzyl)-tetrahydroisoquinolines 27a and 27b. In both cases only one diastereomer was obtained. NOE-experiments confirm Shamma's assignments concerning the stereochemistry. - Various attemps to cleave the dithiane derivative 5 of an α-amino ketone in order to obtain the ketone 6 ...


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Item type:Article
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Alumni or Retired Professors > Prof. Wiegrebe
Dewey Decimal Classification:500 Science > 540 Chemistry & allied sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:15711
Owner only: item control page


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