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Bogner, Ludwig ; Alt, Marco ; Dirscherl, Thomas ; Morgenstern, Ingo ; Latscha, Christof ; Rickhey, Mark

Fast direct Monte Carlo optimization using the inverse kernel approach

Bogner, Ludwig, Alt, Marco, Dirscherl, Thomas, Morgenstern, Ingo, Latscha, Christof and Rickhey, Mark (2009) Fast direct Monte Carlo optimization using the inverse kernel approach. Physics in Medicine and Biology 54 (12), pp. 4051-4067.

Date of publication of this fulltext: 23 Aug 2010 11:58
Article
DOI to cite this document: 10.5283/epub.16265


Abstract

The loss of treatment plan quality after segmentation following fluence optimization is a problem in IMRT. In a previous publication we showed that re-optimization helps to re-establish part of the plan quality. Recently the so-called direct aperture optimization method has been introduced to successfully overcome that difficulty. The aim of the present paper is to present in detail the ...

The loss of treatment plan quality after segmentation following fluence optimization is a problem in IMRT. In a previous publication we showed that re-optimization helps to re-establish part of the plan quality. Recently the so-called direct aperture optimization method has been introduced to successfully overcome that difficulty. The aim of the present paper is to present in detail the integration of the inverse kernel method into direct aperture optimization. It can be shown that this integration leads to a system with high performance with regard to time, while Monte Carlo precision is maintained. The integrated simulated annealing optimization algorithm allows easy adaptation to any multi-leaf collimator and it is open to any complex objective function. Investigations of simulated annealing control parameters are performed to improve the performance. The system denoted by direct Monte Carlo optimization (DMCO) is demonstrated on the Carpet phantom and a clinical prostate case as well. Results are compared to inverse kernel optimizations, showing a remarkable time reduction and simultaneously an improvement in plan quality for the Carpet phantom.



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Details

Item typeArticle
Journal or Publication TitlePhysics in Medicine and Biology
Publisher:IOP PUBLISHING LTD
Place of Publication:BRISTOL
Volume:54
Number of Issue or Book Chapter:12
Page Range:pp. 4051-4067
Date7 July 2009
InstitutionsMedicine > Lehrstuhl für Strahlentherapie
Physics > Institute of Theroretical Physics > Professor Morgenstern
Identification Number
ValueType
10.1088/0031-9155/54/13/007DOI
Classification
NotationType
87.56.ng; 87.55.K-; 87.55.-x; 87.55.Qr; 87.56.DaPACS
KeywordsDIRECT APERTURE OPTIMIZATION; CONFORMAL RADIOTHERAPY; RADIATION-THERAPY; DOSE CALCULATION; PHOTON; IMRT; ALGORITHM; BEAM; OBJECTIVES; TUMORS;
Dewey Decimal Classification500 Science > 530 Physics
600 Technology > 610 Medical sciences Medicine
StatusPublished
RefereedUnknown
Created at the University of RegensburgUnknown
Item ID16265

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