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Bogner, Ludwig ; Alt, Marco ; Dirscherl, Thomas ; Morgenstern, Ingo ; Latscha, Christof ; Rickhey, Mark

Fast direct Monte Carlo optimization using the inverse kernel approach

Bogner, Ludwig, Alt, Marco, Dirscherl, Thomas, Morgenstern, Ingo, Latscha, Christof und Rickhey, Mark (2009) Fast direct Monte Carlo optimization using the inverse kernel approach. Physics in Medicine and Biology 54 (12), S. 4051-4067.

Veröffentlichungsdatum dieses Volltextes: 23 Aug 2010 11:58
Artikel
DOI zum Zitieren dieses Dokuments: 10.5283/epub.16265


Zusammenfassung

The loss of treatment plan quality after segmentation following fluence optimization is a problem in IMRT. In a previous publication we showed that re-optimization helps to re-establish part of the plan quality. Recently the so-called direct aperture optimization method has been introduced to successfully overcome that difficulty. The aim of the present paper is to present in detail the ...

The loss of treatment plan quality after segmentation following fluence optimization is a problem in IMRT. In a previous publication we showed that re-optimization helps to re-establish part of the plan quality. Recently the so-called direct aperture optimization method has been introduced to successfully overcome that difficulty. The aim of the present paper is to present in detail the integration of the inverse kernel method into direct aperture optimization. It can be shown that this integration leads to a system with high performance with regard to time, while Monte Carlo precision is maintained. The integrated simulated annealing optimization algorithm allows easy adaptation to any multi-leaf collimator and it is open to any complex objective function. Investigations of simulated annealing control parameters are performed to improve the performance. The system denoted by direct Monte Carlo optimization (DMCO) is demonstrated on the Carpet phantom and a clinical prostate case as well. Results are compared to inverse kernel optimizations, showing a remarkable time reduction and simultaneously an improvement in plan quality for the Carpet phantom.



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Details

DokumentenartArtikel
Titel eines Journals oder einer ZeitschriftPhysics in Medicine and Biology
Verlag:IOP PUBLISHING LTD
Ort der Veröffentlichung:BRISTOL
Band:54
Nummer des Zeitschriftenheftes oder des Kapitels:12
Seitenbereich:S. 4051-4067
Datum7 Juli 2009
InstitutionenMedizin > Lehrstuhl für Strahlentherapie
Physik > Institut für Theoretische Physik > Professor Morgenstern
Identifikationsnummer
WertTyp
10.1088/0031-9155/54/13/007DOI
Klassifikation
NotationArt
87.56.ng; 87.55.K-; 87.55.-x; 87.55.Qr; 87.56.DaPACS
Stichwörter / KeywordsDIRECT APERTURE OPTIMIZATION; CONFORMAL RADIOTHERAPY; RADIATION-THERAPY; DOSE CALCULATION; PHOTON; IMRT; ALGORITHM; BEAM; OBJECTIVES; TUMORS;
Dewey-Dezimal-Klassifikation500 Naturwissenschaften und Mathematik > 530 Physik
600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin
StatusVeröffentlicht
BegutachtetUnbekannt / Keine Angabe
An der Universität Regensburg entstandenUnbekannt / Keine Angabe
Dokumenten-ID16265

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