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Histamine H4 receptor agonists

Igel, Patrick ; Dove, Stefan ; Buschauer, Armin



Abstract

Since its discovery ten years ago the histamine H4 receptor (H4R) has attracted attention as a potential drug target, for instance, for the treatment of inflammatory and allergic diseases. Potent and selective ligands including agonists are required as pharmacological tools to study the role of the H4R in vitro and in vivo. Many H4R agonists, which were identified among already known histamine ...

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