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Histamine H4 receptor agonists

Igel, Patrick, Dove, Stefan and Buschauer, Armin (2010) Histamine H4 receptor agonists. Bioorganic & Medicinal Chemistry Letters 20 (24), pp. 7191-7199.

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Since its discovery ten years ago the histamine H4 receptor (H4R) has attracted attention as a potential drug target, for instance, for the treatment of inflammatory and allergic diseases. Potent and selective ligands including agonists are required as pharmacological tools to study the role of the H4R in vitro and in vivo. Many H4R agonists, which were identified among already known histamine ...


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Item type:Article
Date:15 December 2010
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer)
Projects:GRK 760, Graduiertenkolleg Medizinische Chemie
Identification Number:
21044842PubMed ID
Related URLs:
Keywords:H4 receptor selectivity; acylguanidines; arylbenzimidazoles; clozapine analogues; cyanoguanidines; indoles; oximes
Dewey Decimal Classification:500 Science > 570 Life sciences
500 Science > 540 Chemistry & allied sciences
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:17078
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