Igel, Patrick, Dove, Stefan and Buschauer, Armin (2010) Histamine H4 receptor agonists. Bioorganic & Medicinal Chemistry Letters 20 (24), pp. 7191-7199.
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Abstract
Since its discovery ten years ago the histamine H4 receptor (H4R) has attracted attention as a potential drug target, for instance, for the treatment of inflammatory and allergic diseases. Potent and selective ligands including agonists are required as pharmacological tools to study the role of the H4R in vitro and in vivo. Many H4R agonists, which were identified among already known histamine ...
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| Item type: | Article | ||||||
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| Date: | 15 December 2010 | ||||||
| Institutions: | Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer) | ||||||
| Projects: | GRK 760, Graduiertenkolleg Medizinische Chemie | ||||||
| Identification Number: |
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| Keywords: | H4 receptor selectivity; acylguanidines; arylbenzimidazoles; clozapine analogues; cyanoguanidines; indoles; oximes | ||||||
| Dewey Decimal Classification: | 500 Science > 570 Life sciences 500 Science > 540 Chemistry & allied sciences | ||||||
| Status: | Published | ||||||
| Refereed: | Yes, this version has been refereed | ||||||
| Created at the University of Regensburg: | Yes | ||||||
| Item ID: | 17078 |
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