Breast cancer inhibiting diastereomeric diacetato[1,2-bis(4-fluorophenyl)ethylenediamine]platinum(II) derivatives: synthesis and studies on the relationship between reactivity and antitumor activity
Gust, Ronald, Krauser, Rudolf, Schmid, Beate und Schönenberger, Helmut (1996) Breast cancer inhibiting diastereomeric diacetato[1,2-bis(4-fluorophenyl)ethylenediamine]platinum(II) derivatives: synthesis and studies on the relationship between reactivity and antitumor activity. Inorganica chimica acta 250 (1-2), S. 203-218.Veröffentlichungsdatum dieses Volltextes: 10 Nov 2010 11:54
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| Dokumentenart | Artikel | ||||
| Titel eines Journals oder einer Zeitschrift | Inorganica chimica acta | ||||
| Verlag: | Elsevier | ||||
|---|---|---|---|---|---|
| Band: | 250 | ||||
| Nummer des Zeitschriftenheftes oder des Kapitels: | 1-2 | ||||
| Seitenbereich: | S. 203-218 | ||||
| Datum | 1996 | ||||
| Zusätzliche Informationen (Öffentlich) | CAN 126:69235 78-7 Inorganic Chemicals and Reactions 105856-26-6 Role: BAC (Biological activity or effector, except adverse), BSU (Biological study, unclassified), BIOL (Biological study) (cytotoxicity for breast cancer); 184895-34-9; 185069-15-2 Role: BAC (Biological activity or effector, except adverse), BSU (Biological study, unclassified), RCT (Reactant), BIOL (Biological study), RACT (Reactant or reagent) (cytotoxicity for breast cancer and reaction with acetic acid or its derivs.); 65-85-0 (Benzoic acid); 76-03-9 (Trichloroacetic acid); 79-11-8 (Monochloroacetic acid); 79-14-1; 79-43-6 (Dichloroacetic acid) Role: RCT (Reactant), RACT (Reactant or reagent) (for prepn. of platinum bis(fluorophenyl)ethylenediamine acetate complex); 105990-74-7 Role: BAC (Biological activity or effector, except adverse), BSU (Biological study, unclassified), PRP (Properties), RCT (Reactant), BIOL (Biological study), RACT (Reactant or reagent) (kinetics of iodide substitution and cytotoxicity for breast cancer); 184895-28-1P; 184895-29-2P; 184895-30-5P; 184895-31-6P; 184895-32-7P; 184895-33-8P; 185069-09-4P; 185069-10-7P; 185069-11-8P; 185069-12-9P; 185069-13-0P; 185069-14-1P Role: BAC (Biological activity or effector, except adverse), BSU (Biological study, unclassified), PRP (Properties), RCT (Reactant), SPN (Synthetic preparation), BIOL (Biological study), PREP (Preparation), RACT (Reactant or reagent) (prepn., kinetics of substitution and breast cancer cytotoxicity of platinum bis(fluorophenyl)ethylenediamine acetate deriv. complexes) | ||||
| Institutionen | Chemie und Pharmazie > Institut für Pharmazie > Entpflichtete oder im Ruhestand befindliche Professoren > Prof. Schönenberger Chemie und Pharmazie > Institut für Pharmazie > Lehrstuhl Pharmazeutische / Medizinische Chemie II (Prof. Buschauer) | ||||
| Identifikationsnummer |
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| Stichwörter / Keywords | Hydrolysis kinetics (of platinum bis(fluorophenyl)ethylenediamine acetate deriv. complexes) Substituent effects (of platinum bis(fluorophenyl)ethylenediamine acetate deriv. complexes vs. breast cancer cytotoxicity) Substitution reaction kinetics (of platinum bis(fluorophenyl)ethylenediamine acetate deriv. complexes with iodide) Antitumor agents (platinum bis(fluorophenyl)ethylenediamine acetate deriv. complexes as) platinum bisfluorophenylethylenediamine acetate deriv prepn cytotoxicity fluorophenylethylenediamine platinum acetate deriv prepn cytotoxicity cytotoxicity platinum bisfluorophenylethylenediamine acetate deriv substituent kinetics substitution platinum bisfluorophenylethylenediamine acetate deriv breast cancer cytotoxicity platinum bisfluorophenylethylenediamine acetate diastereoisomer platinum bisfluorophenylethylenediamine acetate prepn cytotoxicity | ||||
| Dewey-Dezimal-Klassifikation | 500 Naturwissenschaften und Mathematik > 540 Chemie | ||||
| Status | Veröffentlicht | ||||
| Begutachtet | Ja, diese Version wurde begutachtet | ||||
| An der Universität Regensburg entstanden | Ja | ||||
| Dokumenten-ID | 17711 |
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