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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-196414
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.19641
Zusammenfassung
Many physiological variables in hemato-oncology, e.g. the function of liver and kidney and hematopoiesis, show circadian changes. Consequently, the metabolism, elimination and myelotoxicity of cytostatic drugs are subjected to circadian variations in animal and man. Moreover, preliminary clinical data suggest that an optimal circadian timing may even increase the efficacy of anticancer ...
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