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Revised radioreceptor assay for beta 2-adrenoceptors expressed on peripheral mononuclear leukocytes

URN to cite this document:
urn:nbn:de:bvb:355-epub-196523
DOI to cite this document:
10.5283/epub.19652
Haen, Ekkehard ; Liebl, B. ; Lederer, T. ; Pliska, V.
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Date of publication of this fulltext: 18 Feb 2011 10:25


Abstract

Peripheral mononuclear leukocytes (pMNL) bear a population of beta 2-adrenoceptors. Radioreceptor assays with (-)-125Iodocyanopindolol (125I-CYP) are often used to determine the expression of these hormone receptors under physiological and pathological conditions. Doubts on the occurrence of just one class of binding sites as well as the availability of new laboratory equipment prompted us to ...

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