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Prostaglandin I2 release following mesenteric traction during abdominal surgery is mediated by cyclooxygenase-1

Bucher, Michael, Kees, Frieder K., Messmann, Barbara, Lunz, Dirk, Rath, Stephan, Zelenka, Marek, Schlitt, Hans J. and Hobbhahn, Jonny (2006) Prostaglandin I2 release following mesenteric traction during abdominal surgery is mediated by cyclooxygenase-1. European journal of pharmacology 536 (3), pp. 296-300.

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Date of publication of this fulltext: 05 Aug 2009 13:35

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Other URL: http://dx.doi.org/10.1016/j.ejphar.2006.03.009


Abstract

Our study aimed to determine the role of cyclooxygenase-2 in the release of prostaglandin-(PG)-I2 following mesenteric traction during abdominal surgery. In a prospective double-blind, randomized, placebo-controlled study, 40 patients electively scheduled for non-laparoscopic abdominal surgery, were pretreated with the cyclooxygenase-2 inhibitor parecoxib (n=20) or placebo (n=20). Heart rate, ...

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Item type:Article
Date:1 May 2006
Institutions:Medicine > Lehrstuhl für Anästhesiologie
Medicine > Lehrstuhl für Chirurgie
Identification Number:
ValueType
10.1016/j.ejphar.2006.03.009DOI
16581062PubMed ID
Keywords:Mesenteric traction; Cyclooxygenase-inhibitor; Prostaglandin; Hemodynamics; Oxygenation
Dewey Decimal Classification:600 Technology > 610 Medical sciences Medicine
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:1973
Owner only: item control page

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