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Label-free and time-resolved measurements of cell volume changes by surface plasmon resonance (SPR) spectroscopy.

Robelek, Rudolf ; Wegener, Joachim



Abstract

Cell volume and its regulation is one of the key players for cellular integrity and a strong indicator for several cell pathologies. But time-resolved volume measurements of adherently grown mammalian cells using established methods, such as extracellular impedance analysis or light microscopy, are complex and time-consuming. In this study,we demonstrate that surface plasmon resonance ...

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