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Ligand-induced formation of a transient tryptophan synthase complex with aßß subunit stoichiometry

Ehrmann, Alexander, Richter, Klaus, Busch, Florian, Reimann, Julia, Albers, Sonja-Verena and Sterner, Reinhard (2010) Ligand-induced formation of a transient tryptophan synthase complex with aßß subunit stoichiometry. Biochemistry (49), pp. 10842-10853.

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Abstract

The prototypical tryptophan synthases form a stable heterotetrameric RββR complex in which the constituting TrpA and TrpB1 subunits activate each other in a bidirectional manner. The hyperthermophilic archaeon Sulfolobus solfataricus does not contain a TrpB1 protein but instead two members of the phylogenetically distinct family of TrpB2 proteins, which are encoded within (sTrpB2i) and ...

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Item type:Article
Date:2010
Institutions:Biology, Preclinical Medicine > Institut für Biophysik und physikalische Biochemie > Prof. Dr. Reinhard Sterner
Identification Number:
ValueType
10.1021/bi1016815DOI
Dewey Decimal Classification:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:20688
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