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Geisler, Peter ; Meier-Ewert, K. ; Matsubayshi, K.

Rapid eye movements, muscle twitches and sawtooth waves in the sleep of narcoleptic patients and controls

Geisler, Peter, Meier-Ewert, K. und Matsubayshi, K. (1987) Rapid eye movements, muscle twitches and sawtooth waves in the sleep of narcoleptic patients and controls. Electroencephalography and clinical neurophysiology 67 (6), S. 499-507.

Veröffentlichungsdatum dieses Volltextes: 23 Mai 2011 06:27
Artikel
DOI zum Zitieren dieses Dokuments: 10.5283/epub.20915


Zusammenfassung

Seventeen unmedicated patients with narcolepsy-cataplexy and 17 age- and sex-matched controls were recorded polygraphically for 3 consecutive nights. Rapid eye movements (REMs), m. mentalis twitches and sawtooth waves in the EEG were visually scored. REM and twitch densities during REM sleep were significantly higher in the patients than in the controls. The distribution pattern of REMs and ...

Seventeen unmedicated patients with narcolepsy-cataplexy and 17 age- and sex-matched controls were recorded polygraphically for 3 consecutive nights. Rapid eye movements (REMs), m. mentalis twitches and sawtooth waves in the EEG were visually scored. REM and twitch densities during REM sleep were significantly higher in the patients than in the controls. The distribution pattern of REMs and twitches was altered in the patients: twitch density peaked in the first REM period and density of REMs showed an even distribution across all the REM periods of the night. In the controls both REM and twitch density increased from the first to the second REM period. We therefore assume that in the narcoleptics phasic activity of REM sleep is disinhibited. Densities of REMs, twitches and sawtooth waves did not correlate with one another in patients and controls. They appear to be independently regulated. The REM periods of the patients contained 3 times as many waking epochs as those of the controls. This suggests that in narcolepsy the transition REM/waking is selectively facilitated. The REM/NREM ratio of twitch and sawtooth wave densities was the same in patients and controls.



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Details

DokumentenartArtikel
Titel eines Journals oder einer ZeitschriftElectroencephalography and clinical neurophysiology
Verlag:Elsevier
Band:67
Nummer des Zeitschriftenheftes oder des Kapitels:6
Seitenbereich:S. 499-507
Datum1987
InstitutionenMedizin > Lehrstuhl für Psychiatrie und Psychotherapie
Identifikationsnummer
WertTyp
2445541PubMed-ID
Klassifikation
NotationArt
AdultMESH
AgedMESH
Brain/physiopathologyMESH
Cataplexy/physiopathologyMESH
ElectroencephalographyMESH
Eye MovementsMESH
FemaleMESH
HumansMESH
MaleMESH
Middle AgedMESH
Muscles/physiopathologyMESH
Narcolepsy/physiopathologyMESH
Sleep/physiologyMESH
Sleep, REM/physiologyMESH
Dewey-Dezimal-Klassifikation600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin
StatusVeröffentlicht
BegutachtetUnbekannt / Keine Angabe
An der Universität Regensburg entstandenJa
URN der UB Regensburgurn:nbn:de:bvb:355-epub-209152
Dokumenten-ID20915

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