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Electric manipulation and impedance analysis of adherent cells on gold-film electrodes

URN to cite this document:
urn:nbn:de:bvb:355-epub-214904
DOI to cite this document:
10.5283/epub.21490
Stolwijk, Judith Anthea
Date of publication of this fulltext: 11 Jan 2012 06:57


Abstract (English)

This work addresses the electric manipulation, i.e. electroporation or electrofusion, of anchorage-dependent mammalian cells and the subsequent analysis of the cellular response using a well-established impedimetric biosensor (ECIS). Cells were grown to confluence on planar gold-film electrodes, which were used for the application of invasive electric AC pulses as well as for the non-invasive ...

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Translation of the abstract (German)

Die elektrische Manipulation adhärenter Zellen auf leitfähigen Substraten in situ und die anschließende Analyse der Zellantwort mittels Impedanzspektroskopie (ECIS) standen im Vordergrund dieser Arbeit. Dazu wurden konfluente Zellschichten auf planaren Gold-Film Elektroden kultiviert, die zugleich zur Applikation invasiver AC Pulse und zur nichtinvasiven Impedanzanalyse für die Dokumentation der ...

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