Pentón Ribas, David (2012) The role of Task3 potassium channels in the regulation of aldosterone secretion in the adrenal gland. PhD, Universität Regensburg.
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Abstract (English)
About 10% of the patients suffering from arterial hypertension present abnormal production of aldosterone by the adrenal gland. Cell depolarization is a pivotal event in triggering aldosterone secretion in adrenal zona glomerulosa cells when stimulated by angiotensin II and hyperkalemia. These cells, which are strongly hyperpolarized under physiological conditions, have a unique potassium ...

Translation of the abstract (German)
Etwa 10% der Patienten mit Bluthochdruck zeigen krankhafte Veränderungen der Aldosteronproduktion in der Nebenniere. Die Depolarisation ist ein entscheidender Schritt für die Induzierung der Aldosteronausschüttung in adrenalen Zellen der Zona Glomerulosa nach Stimulation mit Angiotensin II oder durch Hyperkaliämie. Diese Zellen sind unter physiologischen Bedingungen stark hyperpolarisiert und ...

Export bibliographical data
Item type: | Thesis of the University of Regensburg (PhD) |
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Date: | 10 February 2012 |
Referee: | Prof. Dr. Richard Warth and Prof. Dr. Karl Kunzelmann and Prof. Dr. Stephan Schneuwly |
Date of exam: | 21 July 2011 |
Institutions: | Biology, Preclinical Medicine > Institut für Physiologie > Prof. Dr. Richard Warth |
Keywords: | Aldosterone, adrenal gland, K2P, KCNK9 |
Dewey Decimal Classification: | 500 Science > 570 Life sciences |
Status: | Published |
Refereed: | Yes, this version has been refereed |
Created at the University of Regensburg: | Yes |
Item ID: | 21666 |