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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-219674
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.21967
Zusammenfassung
Aberrant DNA methylation is often associated with cancer and the formation of tumors; however, the underlying mechanisms, in particular the recruitment and regulation of DNA methyltransferases remain largely unknown. In this study, we identified USP7 as an interaction partner of Dnmt1 and UHRF1 in vivo. Dnmt1 and USP7 formed a soluble dimer complex that associated with UHRF1 as a trimeric complex ...
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