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Lipopeptides are effective stimulators of tyrosine phosphorylation in human myeloid cells

Offermanns, S., Seifert, Roland, Metzger, J. W., Jung, G., Lieberknecht, A., Schmidt, U. and Schultz, Günter (1992) Lipopeptides are effective stimulators of tyrosine phosphorylation in human myeloid cells. Biochemical Journal 282 ( Pt 2, pp. 551-7.

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Date of publication of this fulltext: 24 Jan 2012 08:04

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Abstract

Synthetic lipopeptide analogues of the N-terminus of bacterial lipoprotein are effective activators of macrophages, neutrophils and lymphocytes. We studied the effect of the lipopeptide N-palmitoyl-S-[2,3-bis(palmitoyloxy)-(2RS)-propyl]- (R)-cysteinyl-(S)-seryl-(S)-lysyl-(S)-lysyl-(S)-lysyl-(S)-lysine [Pam3Cys-Ser-(Lys)4] on tyrosine phosphorylation in dibutyryl-cyclic-AMP-differentiated HL-60 ...

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Item type:Article
Date:1992
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmacology and Toxicology (Prof. Schlossmann, formerly Prof. Seifert)
Identification Number:
ValueType
2625355PubMed ID
Classification:
NotationType
Blotting, WesternMESH
Bucladesine/pharmacologyMESH
Cell Differentiation/drug effectsMESH
Cells, CulturedMESH
Electrophoresis, Polyacrylamide GelMESH
GenisteinMESH
HumansMESH
Isoflavones/pharmacologyMESH
Lipoproteins/pharmacologyMESH
Neutrophils/metabolismMESH
Pertussis ToxinMESH
Phosphorylation/drug effectsMESH
Tetradecanoylphorbol Acetate/pharmacologyMESH
Tyrosine/metabolismMESH
Virulence Factors, Bordetella/pharmacologyMESH
Dewey Decimal Classification:600 Technology > 615 Pharmacy
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:23221
Owner only: item control page

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