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Receptor-mediated increases in cytosolic Ca2+ in the human erythroleukaemia cell line involve pertussis toxin-sensitive and -insensitive pathways

URN to cite this document:
urn:nbn:de:bvb:355-epub-232224
Schwaner, I. ; Seifert, Roland ; Schultz, Günter
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Date of publication of this fulltext: 24 Jan 2012 08:07


Abstract

The pluripotent human erythroleukaemia cell line, HEL, possesses erythrocytic, megakaryocytic and macrophage-like properties. With respect to signal transduction, HEL cells have been used as a model system for platelets, but little attention has been paid to their phagocytic properties. We studied the effects of various receptor agonists on the intracellular free Ca2+ concentration ([Ca2+]i) in ...

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