Formation and release of nitric oxide from human neutrophils and HL-60 cells induced by a chemotactic peptide, platelet activating factor and leukotriene B4

URN to cite this document:: urn:nbn:de:bvb:355-epub-232590
DOI to cite this document:: 10.5283/epub.23259

Schmidt, H. H. ; Seifert, Roland ; Böhme, E.

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Date of publication of this fulltext: 24 Jan 2012 13:34

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Abstract

Vascular endothelial cells and neutrophils synthesize and release potent vasodilatatory factors, i.e. endothelium-derived relaxing factors (EDRF) and neutrophil-derived relaxing factors (NDRF). One EDRF has been identified as nitric oxide (NO) derived from arginine. We studied the synthesis and release of NO from human neutrophils stimulated with the chemotactic peptide ...