Go to content
UR Home

Partial inhibition of human neutrophil activation by FK-506 at supratherapeutic concentrations

URN to cite this document:
urn:nbn:de:bvb:355-epub-232887
Wenzel-Seifert, Katharina ; Seifert, Roland
[img]
Preview
PDF
(827kB)
Date of publication of this fulltext: 25 Jan 2012 10:40


Abstract

The macrolide, FK-506, is a potent and effective inhibitor of lymphocyte activation. We studied the effects of FK-506 on human neutrophil activation induced by chemoattractants and by various substances which circumvent receptor stimulation. After preincubation for 5 min at 37 degrees C, FK-506 (1 microM) inhibited N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMet-Leu-Phe)- or ...

plus


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons