Naim, M., Seifert, Roland, Nürnberg, B., Grünbaum, L. und Schultz, Günter
Some taste substances are direct activators of G-proteins.
The Biochemical journal 297 ( Pt 3, S. 451-454.
Zum PubMed-Eintrag dieses Artikels
Amphiphilic substances may stimulate cellular events through direct activation of G-proteins. The present experiments indicate that several amphiphilic sweeteners and the bitter tastant, quinine, activate transducin and Gi/Go-proteins. Concentrations of taste substances required to activate G-proteins in vitro correlated with those used to elicit taste. These data support the hypothesis that amphiphilic taste substances may elicit taste through direct activation of G-proteins.
Bibliographische Daten exportieren