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Human neutrophils and HL-60 cells do not possess alpha 2-adrenoceptors

URN to cite this document:
urn:nbn:de:bvb:355-epub-233048
Musgrave, I. F. ; Seifert, Roland
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Date of publication of this fulltext: 26 Jan 2012 07:30


Abstract

Human neutrophils have been reported to possess both alpha 2- and beta 2-adrenoceptors. While activation of beta 2-adrenoceptors is known to inhibit N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP)-induced superoxide anion (O2-) production, the functional role of alpha 2-adrenoceptors is not known. We studied the effects of a range of structurally unrelated alpha 2-adrenoceptor agonists on ...

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