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Ascorbic Acid Enhances Adipogenesis of Bone Marrow-Derived Mesenchymal Stromal Cells

Weiser, Barbara ; Sommer, Florian ; Neubauer, M. ; Seitz, Anna Katharina ; Teßmar, Jörg ; Göpferich, Achim ; Blunk, Torsten



Abstract

A prerequisite to successfully engineer cell-based adipose tissue surrogates is the evaluation of in vitro culture conditions that facilitate expansion of primary precursor cells under retention of their adipogenic potential and that enable a large fraction of the heterogeneous cell pool to undergo adipogenesis upon respective stimuli. Ascorbic acid (AA) was reported to enhance differentiation of ...

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