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An examination of TOR1A variants in recurrent major depression

URN to cite this document:
urn:nbn:de:bvb:355-epub-236169
Heining, F. A. ; Langguth, Berthold ; Eichhammer, Peter ; Domani, M. ; Hajak, Göran ; Sand, Philipp G.
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Date of publication of this fulltext: 21 Mar 2012 10:12


Abstract

Background: Observations of comorbid depression in subjects with primary dystonia have suggested a dual role for the TOR1A gene in mood disorders and movement disorders. We conducted a systematic search for carriers of the ∆GAG deletion and for other variants in TOR1A exon 5 among 414 Caucasian subjects with recurrent major depression from the Upper Palatinate. Findings: Allele frequencies were ...

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