Go to content
UR Home

Dimerization determines substrate specificity of a bacterial prenyltransferase

Peterhoff, David ; Zellner, Hermann ; Guldan, Harald ; Merkl, Rainer ; Sterner, Reinhard ; Babinger, Patrick



Abstract

We have identified the native dimer interface of heptaprenylglyceryl phosphate synthase PcrB from the bacterium Bacillus subtilis and analyzed the significance of oligomer formation for stability and catalytic activity. Computational methods predicted two different surface regions of the PcrB protomer that could be responsible for dimer formation. These bona fide interfaces were assessed both in ...

plus


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de

Dissertations: dissertationen@ur.de

Research data: daten@ur.de

Contact persons