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Polymeric micelles for solubilization and targeting of hydrophobic drugs

Miller, Tobias (2013) Polymeric micelles for solubilization and targeting of hydrophobic drugs. PhD, Universität Regensburg.

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Date of publication of this fulltext: 11 Jan 2013 09:32

Abstract (English)

This thesis focussed on the encapsulation of hydrophobic drugs into polymeric micelles and was intended to show the strengths and limitations of these self-assembling systems in terms of solubilization and drug targeting. Characterization of hydrophobic drug solubilization prior to intravenous injection was one of the key goals of this thesis. For this purpose a novel drug loading procedure was ...

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Translation of the abstract (German)

Diese Dissertation beschäftigt sich mit der Verkapselung hydrophober Wirkstoffe in Polymer-basierenden Mizellen und hatte das Ziel, Stärken und Schwächen dieser selbst-assoziierenden Systeme hinsichtlich Solubilisierung und Drug Targeting aufzuzeigen. Die Charakterisierung der Solubiliserung vor Injektion dieser Partikel war eines der Hauptziele der Dissertation. Dafür wurde ein neues Verfahren ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:11 January 2013
Referee:Prof. Dr. Sigurd Elz and Prof. Dr. Achim Göpferich and PD Dr. Rainer Müller and Prof. Dr. Frank-Michael Matysik
Date of exam:27 June 2012
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Technology (Prof. Göpferich)
Keywords:drug targeting, hydrophobic drugs, polyethylene glycol derivatives, polymeric micelles, FRET
Dewey Decimal Classification:600 Technology > 615 Pharmacy
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:25345
Owner only: item control page

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