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Polymeric micelles for solubilization and targeting of hydrophobic drugs

Miller, Tobias (2013) Polymeric micelles for solubilization and targeting of hydrophobic drugs. PhD, Universität Regensburg.

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Date of publication of this fulltext: 11 Jan 2013 09:32

Abstract (English)

This thesis focussed on the encapsulation of hydrophobic drugs into polymeric micelles and was intended to show the strengths and limitations of these self-assembling systems in terms of solubilization and drug targeting. Characterization of hydrophobic drug solubilization prior to intravenous injection was one of the key goals of this thesis. For this purpose a novel drug loading procedure was ...


Translation of the abstract (German)

Diese Dissertation beschäftigt sich mit der Verkapselung hydrophober Wirkstoffe in Polymer-basierenden Mizellen und hatte das Ziel, Stärken und Schwächen dieser selbst-assoziierenden Systeme hinsichtlich Solubilisierung und Drug Targeting aufzuzeigen. Die Charakterisierung der Solubiliserung vor Injektion dieser Partikel war eines der Hauptziele der Dissertation. Dafür wurde ein neues Verfahren ...


Export bibliographical data

Item type:Thesis of the University of Regensburg (PhD)
Date:11 January 2013
Referee:Prof. Dr. Sigurd Elz and Prof. Dr. Achim Göpferich and PD Dr. Rainer Müller and Prof. Dr. Frank-Michael Matysik
Date of exam:27 June 2012
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical Technology (Prof. Göpferich)
Keywords:drug targeting, hydrophobic drugs, polyethylene glycol derivatives, polymeric micelles, FRET
Dewey Decimal Classification:600 Technology > 615 Pharmacy
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Partially
Item ID:25345
Owner only: item control page


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