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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-254216
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.25421
Zusammenfassung
Degeneration of nigrostriatal dopaminergic neurons is the primary histopathological feature of Parkinson's disease. The neurotoxin MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) induces a neurological syndrome in man and non-human primates very similar to idiopathic Parkinson's disease by selectively destroying dopaminergic nigrostriatal neurons. This gives rise to the hypothesis that ...
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