Fronto-striatal cognitive deficits at different stages of Parkinson's disease

URN to cite this document:: urn:nbn:de:bvb:355-epub-254266
DOI to cite this document:: 10.5283/epub.25426

Owen, A. M. ; James, M. ; Leigh, P. N. ; Summers, B. A. ; Marsden, C. D. ; Quinn, N. P. ; Lange, Klaus W. ; Robbins, T. W.

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Date of publication of this fulltext: 20 Jul 2012 11:27

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Abstract

Groups of patients with idiopathic Parkinson's disease, either medicated or unmedicated, were compared with matched groups of normal controls on a computerized battery previously shown to be sensitive to frontal lobe dysfunction, including tests of planning, spatial working memory and attentional set-shifting. In a series of problems based on the 'Tower of London' test, medicated patients with ...