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Motor activity following the administration of selective D-1 and D-2 dopaminergic drugs to normal common marmosets

URN to cite this document:
urn:nbn:de:bvb:355-epub-254415
Löschmann, P. A. ; Smith, L. A. ; Lange, Klaus W. ; Jaehnig, P. ; Jenner, P. ; Marsden, C. D.
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Date of publication of this fulltext: 20 Jul 2012 10:03


Abstract

In normal common marmosets administration of the D-1/D-2 agonist apomorphine or the selective D-2 agonist quinpirole caused a dose-dependent increase in motor activity and induced stereotyped behaviour. Both the selective D-2 antagonist raclopride and the selective D-1 antagonist SCH 23390 inhibited normal locomotor activity and induced catalepsy. Quinpirole- and apomorphine-induced motor ...

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