ATP-binding cassette transporters in immortalised human brain microvascular endothelial cells in normal and hypoxic conditions

URN to cite this document:: urn:nbn:de:bvb:355-epub-258477
DOI to cite this document:: 10.5283/epub.25847

Lindner, Christian ; Sigrüner, Alexander ; Walther, Franziska ; Bogdahn, Ulrich ; Couraud, Pierre O. ; Schmitz, Gerd ; Schlachetzki, Felix

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Date of publication of this fulltext: 07 Sep 2012 06:48

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Abstract

Background Rapid reperfusion following ischemia is the most effective therapy in stroke therapy. However, the success may be compromised by ischemia & reperfusion (I/R) injury and at the human blood-brain barrier (BBB), therefore the effects on transendothelial transport are of special interest. Current studies suggest the ATP-binding cassette (ABC) transporters to be regulated upon ischemic ...