Resequencing of the auxiliary GABAB receptor subunit gene KCTD12 in chronic tinnitus

URN to cite this document:: urn:nbn:de:bvb:355-epub-258544
DOI to cite this document:: 10.5283/epub.25854

Sand, Philipp G. ; Langguth, Berthold ; Itzhacki, Jacob ; Bauer, Angelika ; Geis, Sandra ; Cárdenas-Conejo, E. ; Pimentel, Vanessa ; Kleinjung, Tobias ; Zuge, Elisabeth

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Date of publication of this fulltext: 07 Sep 2012 06:35

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Abstract

Tinnitus is a common and often incapacitating hearing disorder marked by the perception of phantom sounds. Susceptibility factors remain largely unknown but GABAB receptor signaling has long been implicated in the response to treatment and, putatively, in the etiology of the disorder. We hypothesized that variation in KCTD12, the gene encoding an auxiliary subunit of GABAB receptors, could help ...