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The levels of clarithromycin and its 14-hydroxy metabolite in the lung

Honeybourne, D., Kees, Frieder K., Andrews, J. M., Baldwin, D. and Wise, R. (1994) The levels of clarithromycin and its 14-hydroxy metabolite in the lung. The European respiratory journal 7 (7), pp. 1275-1280.

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Abstract

Clarithromycin is a new macrolide that has a longer half-life than erythromycin and is claimed to reach higher tissue concentrations. We aimed to investigate whether, following oral administration, the drug and its 14-hydroxy metabolite reach levels in lung tissue that are likely to be clinically effective against common respiratory pathogens. Ten patients undergoing diagnostic bronchoscopy ...

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Item type:Article
Date:1994
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmacology and Toxicology (Prof. Schlossmann, formerly Prof. Seifert)
Identification Number:
ValueType
7925906PubMed ID
Classification:
NotationType
Clarithromycin/pharmacokineticsMESH
FemaleMESH
HumansMESH
Lung/metabolismMESH
MaleMESH
Dewey Decimal Classification:600 Technology > 615 Pharmacy
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:26822
Owner only: item control page

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