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Clarithromycin, ein neues Makrolid-Antibiotikum. Wirksamkeit bei puerperalen Infektionen und Übertritt in die Muttermilch [Clarithromycin, a new macrolide antibiotic. Effectiveness in puerperal infections and pharmacokinetics in breast milk]

URN to cite this document:
urn:nbn:de:bvb:355-epub-268244
Sedlmayr, T. ; Petersen, F. ; Raasch, W. ; Kees, Frieder K.
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Date of publication of this fulltext: 29 Nov 2012 12:48


Abstract

The aims of this study were, to determine the pharmacokinetic parameters of clarithromycin and to study the passage of the drug into breast milk. Twelve patients (age 24 to 38; weight 44 to 83 kg), suffering from puerperal infections, were treated orally with 250 mg clarithromycin b.i.d. for 6 days. Samples of blood and breast milk were taken at timed intervals. The specimens were assayed for ...

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