Pharmacokinetic parameters and haemodynamic actions of midodrine in young volunteers

URN to cite this document:: urn:nbn:de:bvb:355-epub-268258
DOI to cite this document:: 10.5283/epub.26825

Grobecker, H. F. ; Kees, Frieder K.

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Date of publication of this fulltext: 29 Nov 2012 13:02

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Abstract

In two groups of volunteers pharmacological parameters of the antihypotensive drug midodrine have been investigated. The first group of 12 male healthy volunteers received 2.5 mg midodrine hydrochloride intravenously, as drinking solution or as tablet according to a randomized cross-over design. Plasma and urine samples were analyzed for midodrine and its main metabolite ST 1059 by ...