Cardiovascular parameters and catecholamines in volunteers during passive orthostasis. Influence of antihypotensive drugs

URN to cite this document:: urn:nbn:de:bvb:355-epub-268260
DOI to cite this document:: 10.5283/epub.26826

Dominiak, P. ; Kees, Frieder K. ; Welzel, D. ; Grobecker, H.

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Date of publication of this fulltext: 29 Nov 2012 12:46

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Abstract

To evaluate the therapeutic value of various antihypotensive agents we investigated amezinium (AMZ; CAS 30578-37-1), dihydroergotamine (DHE; CAS 511-12-6), midodrine (MDD; CAS 42794-76-3), and oxilofrine (OXF; CAS 365-26-4) in volunteers during passive orthostasis in a randomized double-blind study against placebo (PCB). Blood pressure, heart rate, and circulating catecholamines were determined ...