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Strukturelle Charakterisierung eines unbekannten Metaboliten von Ciprofloxacin [Structural characterization of an unknown metabolite of ciprofloxacin]

Kees, Frieder K., Raasch, W. and Grobecker, H.F. (1992) Strukturelle Charakterisierung eines unbekannten Metaboliten von Ciprofloxacin [Structural characterization of an unknown metabolite of ciprofloxacin]. Arzneimittel-Forschung 42 (4), pp. 570-575.

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Abstract

The chemical structure of an unknown metabolite of ciprofloxacin (CAS 85721-33-1) is characterized by means of reversed phase ion pair liquid chromatography, absorption and fluorescence spectroscopy, partition coefficients as well as chemical and enzymatic hydrolytic degradation. A chemical structure of the unknown metabolite is proposed: N-formyl-desethylen-ciprofloxacin. It can be formed as an ...

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Item type:Article
Date:1992
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmacology and Toxicology (Prof. Schlossmann, formerly Prof. Seifert)
Identification Number:
ValueType
1642685PubMed ID
Classification:
NotationType
BiotransformationMESH
Chromatography, High Pressure LiquidMESH
Ciprofloxacin/pharmacokineticsMESH
HumansMESH
Oxidation-ReductionMESH
Spectrometry, FluorescenceMESH
Dewey Decimal Classification:600 Technology > 615 Pharmacy
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:26827
Owner only: item control page

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