Strukturelle Charakterisierung eines unbekannten Metaboliten von Ciprofloxacin [Structural characterization of an unknown metabolite of ciprofloxacin]

URN to cite this document:: urn:nbn:de:bvb:355-epub-268271
DOI to cite this document:: 10.5283/epub.26827

Kees, Frieder K. ; Raasch, W. ; Grobecker, H. F.

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Date of publication of this fulltext: 29 Nov 2012 12:45

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Abstract

The chemical structure of an unknown metabolite of ciprofloxacin (CAS 85721-33-1) is characterized by means of reversed phase ion pair liquid chromatography, absorption and fluorescence spectroscopy, partition coefficients as well as chemical and enzymatic hydrolytic degradation. A chemical structure of the unknown metabolite is proposed: N-formyl-desethylen-ciprofloxacin. It can be formed as an ...