Naber, K. G., Sörgel, F., Kees, Frieder K., Schumacher, H., Metz, R. und Grobecker, H.
In-vitro activity of fleroxacin against isolates causing complicated urinary tract infections and concentrations in seminal and prostatic fluid and in prostatic adenoma tissue.
The Journal of antimicrobial chemotherapy 22 Suppl D, S. 199-207.
Zum PubMed-Eintrag dieses Artikels
Fleroxacin is a new fluoroquinolone with a broad antibacterial spectrum and a serum half-life of about 8-12 h. Eighty percent of 400 isolates from complicated or hospital-acquired urinary tract infections were inhibited by a concentration of 1 mg/l and 95% by 4 mg/l. As with other quinolones, fleroxacin is less active in acid urine (pH 5.4) than in Mueller-Hinton broth (pH 7.4). In 12 healthy ...
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