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Inhibition of monoamine oxidase by viloxazine in rats

Martinez, C., Dominiak, P., Kees, Frieder K. and Grobecker, H. (1986) Inhibition of monoamine oxidase by viloxazine in rats. Arzneimittel-Forschung 36 (5), pp. 800-803.

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Abstract

Biochemical and pharmacological investigations about the effect of the antidepressant drug viloxazine (Vivalan) on catecholamine metabolism in rats led to the following results: Viloxazine exerts a dose and time dependent inhibition of monoamine oxidase activity of brain and liver mitochondrial fraction and tissue homogenates of hypothalamus, heart, liver, and adrenal glands, both in vitro and ...

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Item type:Article
Date:1986
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmacology and Toxicology (Prof. Schlossmann, formerly Prof. Seifert)
Identification Number:
ValueType
2425816PubMed ID
Classification:
NotationType
AnimalsMESH
Brain Chemistry/drug effectsMESH
Catecholamines/metabolismMESH
Hydroxyindoleacetic Acid/metabolismMESH
Hypothalamus/enzymologyMESH
KineticsMESH
MaleMESH
Mitochondria/enzymologyMESH
Monoamine Oxidase InhibitorsMESH
Morpholines/pharmacologyMESH
RatsMESH
Rats, Inbred StrainsMESH
Serotonin/metabolismMESH
Viloxazine/pharmacologyMESH
Dewey Decimal Classification:600 Technology > 615 Pharmacy
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:26849
Owner only: item control page

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