Inhibition of monoamine oxidase by viloxazine in rats

URN to cite this document:: urn:nbn:de:bvb:355-epub-268490
DOI to cite this document:: 10.5283/epub.26849

Martinez, C. ; Dominiak, P. ; Kees, Frieder K. ; Grobecker, H.

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Date of publication of this fulltext: 29 Nov 2012 12:38

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Abstract

Biochemical and pharmacological investigations about the effect of the antidepressant drug viloxazine (Vivalan) on catecholamine metabolism in rats led to the following results: Viloxazine exerts a dose and time dependent inhibition of monoamine oxidase activity of brain and liver mitochondrial fraction and tissue homogenates of hypothalamus, heart, liver, and adrenal glands, both in vitro and ...