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High-performance liquid chromatography analysis of mezlocillin, piperacillin, their degradation products, and of ioxitalamic acid in plasma and urine of healthy volunteers

Kees, Frieder K., Naber, K. G., Bartoschik-Wich, B., Stockmann, P., Meyer, G. P. and Grobecker, H. (1985) High-performance liquid chromatography analysis of mezlocillin, piperacillin, their degradation products, and of ioxitalamic acid in plasma and urine of healthy volunteers. Arzneimittel-Forschung 35 (7), pp. 1099-1104.

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Abstract

In plasma and urine of 10 healthy volunteers after intravenous administration of 4 g mezlocillin and piperacillin, respectively, the parent compounds as well as degradation products were assayed by high-performance liquid chromatography. Ioxitalamic acid, a renal contrast medium, was administered simultaneously, in order to measure the glomerular filtration rate, and to control the collection of ...

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Item type:Article
Date:1985
Institutions:Chemistry and Pharmacy > Institute of Pharmacy > Pharmacology and Toxicology (Prof. Schlossmann, formerly Prof. Seifert)
Identification Number:
ValueType
4052146PubMed ID
Classification:
NotationType
AdultMESH
Chromatography, High Pressure LiquidMESH
FemaleMESH
HumansMESH
Iothalamic Acid/urineMESH
KineticsMESH
MaleMESH
Mezlocillin/urineMESH
Piperacillin/urineMESH
Dewey Decimal Classification:600 Technology > 615 Pharmacy
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Unknown
Item ID:26853
Owner only: item control page

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