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[3H]UR-PLN196: A Selective Nonpeptide Radioligand and Insurmountable Antagonist for the Neuropeptide Y Y2 Receptor

Pluym, Nikola ; Baumeister, Paul ; Keller, Max ; Bernhardt, Günther ; Buschauer, Armin



Abstract

Attachment of a [2,3-(3)H]propionyl group through an appropriate linker to the guanidine group of an (S)-argininamide-type neuropeptide Y (NPY) Y(2) receptor antagonist resulted in a subtype-selective radioligand.


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