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Molecular characterization of human regulatory and conventional T cells

Schmidl, Christian (2014) Molecular characterization of human regulatory and conventional T cells. PhD, Universität Regensburg.

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Date of publication of this fulltext: 09 Jan 2014 16:34

Abstract (English)

Complex multicellular organisms give rise to a wide range of cell types and tissues, even though all the cells share the same DNA sequence. Key to this diversity is differential gene expression in the different types of cells. Gene expression is orchestrated by regulatory DNA sequences, which can be bound by transcription factors mediating the activation or repression of a target gene. These ...

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Translation of the abstract (German)

Obwohl in jeder Zelle dieselbe Erbinformation (DNS-Sequenz) vorliegt, bestehen komplexe Organismen aus einer Vielzahl von Zelltypen und Geweben mit den unterschiedlichsten Eigenschaften. Der Schlüssel zu dieser Vielfalt liegt in der Fähigkeit der verschiedenen Zelltypen, die Erbinformation zelltypspezifisch abzulesen. Das Ablesen oder die sogenannte Expression von Genen wird durch regulatorische ...

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Item type:Thesis of the University of Regensburg (PhD)
Date:9 January 2014
Referee:Prof. Dr. Michael Rehli
Date of exam:1 February 2013
Institutions:Medicine > Lehrstuhl für Innere Medizin III (Hämatologie und Internistische Onkologie)
Biology, Preclinical Medicine > Institut für Biochemie, Genetik und Mikrobiologie > Lehrstuhl für Biochemie III
Keywords:regulatory T cell, conventional T cell, epigenetics, DNA methylation, histone modifications, gene expression, chromatin, transcription factor, Transkriptionsfaktor, regulatorische T Zelle, konventionelle T Zelle, Epigenetik, Chromatin, Genexpression, Histonmodifikationen, DNA Methylierung
Dewey Decimal Classification:500 Science > 570 Life sciences
Status:Published
Refereed:Yes, this version has been refereed
Created at the University of Regensburg:Yes
Item ID:27348
Owner only: item control page

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