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Penetration of moxifloxacin into liver tissue

Justinger, Christoph ; Schilling, Martin K. ; Kees, Martin G. ; Kauffels, Anne ; Hirschmann, Katrin ; Kopp, Berit ; Kees, Frieder K. ; Kollmar, Otto


Moxifloxacin is considered for treatment of pyogenic liver abscesses as well as antibiotic prophylaxis in the case of hepatobiliary interventions. The aim of this study was to provide data on the pharmacokinetic (PK) profile of moxifloxacin in serum and liver tissue of patients undergoing liver resection due to primary or secondary tumours of the liver. Patients scheduled for liver resection ...


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