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cGMP-dependent Protein Kinase Inhibitors in Health and Disease

URN to cite this document:
urn:nbn:de:bvb:355-epub-282627
Wolfertstetter, Stefanie ; Huettner, Johannes Philip ; Schlossmann, Jens
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Date of publication of this fulltext: 21 Jun 2013 12:41


Abstract

cGMP-dependent protein kinases (PKG) exhibit diverse physiological functions in the mammalian system e.g., in vascular and gastrointestinal smooth muscles, in platelets, in kidney, in bone growth, nociception and in the central nervous system. Furthermore, PKG were found in insects and in the malaria parasite Plasmodium falciparum. Two different genes of PKG exist: a) the PKG-I gene that is ...

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